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HyperProbe project successfully concludes first year with promising achievements

18 December 2023

illustration of a human brain

The EU-funded project has marked the conclusion of its inaugural year with significant progress towards revolutionising neurosurgery through advanced functional-guided neuronavigational imaging.

The project 鈥Transforming brain surgery by advancing functional-guided neuronavigational imaging鈥 aims to develop a novel cost-effective, transportable, compact optical imaging system (鈥溾) to measure brain function during surgery to achieve better guidance during brain tumour removal by 2027, significantly improving surgical outcomes for patients.

The HyperProbe consortium brings together researchers, engineers and physicists in the field of optical imaging and medical device development, computer scientists, artificial intelligence experts, neurologists, and neurosurgeons from eight academic institutions and industry partners from across Europe, including 果冻影院.聽

HyperProbe Logo

Year One Achievements:

In the past year, the HyperProbe consortium, coordinated and led by the University of Florence, has made remarkable advances in the design and development of the HyperProbe1 system. This high-performance, versatile, laboratory HSI setup for investigating novel biomarkers for glioma detection and optimisation of hyperspectral parameters has shown promising preliminary results for the clinical translation of its future prototypes. The preliminary testing has allowed the Consortium to study the areas in need for further optimisation for the final HyperProbe device. Another achievement in the first year of the project was the development of a computation tool able to simulate light diffusion through a digital brain incorporating realistic instrument specifications, developed by 果冻影院.

, who leads the 果冻影院 researchers,聽welcomes a new PhD student,聽Angelos聽Artemiou, to the team:

"As we move聽into the second year of the Hyperprobe project, the 果冻影院 team is very happy to welcome Angelos Artemiou to the project. Angelos will be working on the development of realistic optical phantoms simulating the head and brain.鈥澛

Prof Ilias Tachtsidis, 果冻影院 Lead Coordinator

These significant advancements in the project鈥檚 first year will help the Consortium build on this accumulated knowledge to produce the final device, HyperProbe2, ready for clinical study.

Outlook for Year Two:

As the HyperProbe project enters its second year, the consortium is ready for even greater accomplishments. The focus will be on refining the HyperProbe system based on insights gained during the initial phases. Anticipated milestones for the upcoming year include:

  • Continue the preliminary testing and characterisation of HyperProbe1
  • Develop the software tools for deep learning-based reconstruction of optical images and quantitative parameters maps.
  • The development of Automatic image-processing pipelines for registration of intraoperative and preoperative optical imaging modalities.

The HyperProbe project remains committed to its goal of transforming brain surgery and improving patient outcomes. Through continued dedication, collaboration, and innovation, the consortium aims to bring this cutting-edge technology to the forefront of neurosurgical practice.

The first year in the development of HyperProbe has provided very promising initial results towards unlocking and exploiting the incredible potential of hyperspectral imaging to impact neuronavigation in current surgical practice, and we are looking forward to continue successfully for the upcoming next steps鈥 鈥 Francesco S. Pavone (UNIFI)

Background

To achieve their ambitious goal, the HyperProbe consortium brings together researchers, engineers and physicists in the field of optical imaging and medical device development, computer scientists, artificial intelligence experts, neurologists, and neurosurgeons from eight academic institutions and industry partners from across Europe: Universit谩 degli studi di Firenze, IT, Emoled, IT, Technische Universit盲t M眉nchen, DE, Universit茅 Lyon 1 Claude Bernard, FR, Centre National de la Recherche Scientifique, FR, Azienda Ospedaliera Universitaria di Careggi, IT, European Institute for Biomedical Imaging Research, AT, Hospices Civils de Lyon, FR, 果冻影院, UK. The project will run from October 2022 to September 2027.

EU-funding

The HyperProbe project receives funding from the European Union鈥檚 Horizon Europe research and innovation programme under grant agreement No 101071040.The UK participant (果冻影院) in the Horizon Europe Project 鈥楬yperProbe鈥 is supported by UKRI grant numbers 10048387.

Disclaimer

Funded by the European Union. Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union or the European Innovation Council and SMEs Executive Agency (EISMEA). Neither the European Union nor the granting authority can be held responsible for them.

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