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果冻影院 Researchers part of EU project to radically improve brain surgery navigation

19 December 2022

illustration of a human brain

The new EU-funded project 鈥溾 will develop a novel cost-effective, transportable, compact optical imaging system (鈥淗yperProbe鈥) to measure brain function during surgery to achieve better guidance during brain tumour removal by 2027, significantly improving surgical outcomes for patients.

When removing brain tumours, Neurosurgeons must聽differentiate between healthy tissue and the tumour and ensure the integrity of the patient鈥檚 brain function during and after surgery. They also need to identify tumour borders to precisely remove the tumour while saving healthy tissue. To increase positive outcomes during surgery, surgeons require neuro-navigation systems to provide them with quantitative, accurate and real-time information on brain activity and tumour location.

Current approaches present major limitations as they are very invasive, do not provide the surgeons with sufficient information, or cannot assess brain activity accurately enough. Moreover, biochemical characterisation of the tumour is needed for more precise tumour border detection, which can be achieved through advanced imaging.

The HyperProbe consortium brings together researchers, engineers and physicists in the field of optical imaging and medical device development, computer scientists, artificial intelligence experts, neurologists, and neurosurgeons from eight academic institutions and industry partners from across Europe, including 果冻影院. The consortium will propose a new multifunctional hyperspectral imaging device to provide real-time, quantitative, and accurate assessment of brain activity and tumour borders intraoperatively. Using an optical, contactless, and hence minimally invasive neuroimaging approach, the device will provide exhaustive biochemical information on the brain tissue and tumour features during surgery and cortical activity stimulation. The device will be cost- effective, transportable, easy-to-use and integrate with existing clinical instrumentation that is fully suitable for the operating room.

果冻影院 Physics and Biomedical Engineering Professor and Lead Coordinator from 果冻影院,聽, commented:

After a very competitive process I聽was very pleased that our Hyperprobe project was funded. We will for the first time translate the hyperspectral optical technologies for monitoring and imaging metabolism that we developed in our lab, to assist neurosurgery for glioblastoma tumour borders identification.

The 果冻影院 team comprises of and from the Biomedical Optics Research Laboratory (BORL) and colleagues from the Wellcome / EPSRC Centre for Interventional and Surgical Sciences (WEISS). The project will run from October 2022 to September 2027.聽

UK participants in Horizon Europe Project 果冻影院 (果冻影院) are supported by UKRI grant number 10048387 (果冻影院).

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