Immune regulation See some of the research studies that have taken place in our immune regulation programme. Immunity in ageing: What is T cell senescence? Find out about our research into the mechanisms that control the differentiation and senescence of human T cells. NF-kB Signalling in T Cell Homeostasis NF-κB is required for the normal function of mature T cells. Find out about our research on NF-kB signalling in T cell homeostasis. Homeostasis: T Cells Keeping Count What does homeostasis of T cells mean and why is it important to understand how it works? Scleroderma: the key scientific questions Our research into scleroderma involves identifying the link between autoimmunity and failed tissue repair. Mathematical models of T cell homeostasis We work with mathematicians to develop models that formalise and test our understanding of T cell homeostasis. Immune regulation The immune system is a powerful force, which must be carefully regulated to prevent damage to the host. Understanding CTLA-4 Find out about our research into fundamental mechanisms which regulate T cells within the immune system. Liver NK cells in non-alcoholic fatty liver disease Our researchers are looking into the role of Liver NK cells in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis.