Close
The centre publishes work in a variety of fields including: Rhinology, Head and Neck Cancer, Smell Dysfunction, HPV induced Oropharyngeal Cancer and Betel Nut and Oral Cancer.
1. HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management. M. Lechner, et al. Nature Reviews of Clinical Oncology. 2022; 19(5):306-327; doi: 10.1038/s41571-022-00603-7.听
2. DNA methylation-based classification of sinonasal tumors. P. Jurmeister, 鈥� , M. Lechner, ... , D. Capper. Nature Communications. 2022; 13(1):7148. doi: 10.1038/s41467-022-34815-3..
3. Signatures of copy number alterations in human cancer. C.D. Steele, 鈥� , M. Lechner, 鈥� , N. Pillay; Nature. 2022; doi: 10.1038/s41586-022-04738-6.听
4. A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution. T. Zhu, ... , M. Lechner, ... , A.E. Teschendorff. Nature Methods. 2022;19(3):296-306; doi: 10.1038/s41592-022-01412-7.
5. Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. M. Lechner, et al.; Nature Communications. 2021; 12(1):117. doi: 10.1038/s41467-020-20308-8.
6. The COVANOS trial 鈥� insight into post-COVID olfactory dysfunction and the role of smell training. M. Lechner, et al. Rhinology. 2022; doi: 10.4193/Rhin21.470.听
7. Clinical Outcomes, Kadish-INSICA Staging and Therapeutic Targeting of SSTR2 in Olfactory Neuroblastoma. M. Lechner, et al.; European Journal of Cancer. 2022; 162:221-236; doi: 10.1016/j.ejca.2021.09.046.
8. Anosmia and hyposmia in health-care workers with undiagnosed SARS-CoV-2 infection. M.Lechner et al.; The Lancet Microbe. 2020, 1(4): e150.
9. Olfactory Loss of Function as a Possible Symptom of COVID-19. M. Lechner, Z.M. Patel, C. Philpott, V.J. Lund; JAMA Otolaryngology - Head and Neck Surgery. 2020,10.1001/jamaoto.2020.1589. doi:10.1001/jamaoto.2020.1589
10. Early detection of HPV-associated oropharyngeal cancer. M. Lechner et al.; The Lancet. 2019; 393(10186):2123.
11. Betel nut chewing in high income countries鈥攍ack of awareness and regulation. M. Lechner et al.; The Lancet Oncology. 2019;20(2):181-183.
12. Gender-neutral HPV vaccination in the UK, rising male oropharyngeal cancer rates, and lack of HPV awareness. M. Lechner et al.; The Lancet Infectious Diseases. 2019; 19(2):131-132.
13. Pan-cancer deconvolution of tumour composition using DNA methylation. A. Chakravarthy, 鈥� , M. Lechner, 鈥�, T.R. Fenton. Nature Communications. 2018; 13;9(1): 3220.
14. DNA methylation-based reclassification of olfactory neuroblastoma. D. Capper, 鈥� , M. Lechner, 鈥� , U. Sch眉ller. Acta Neuropatholica. 2018. doi: 10.1007/s00401-018-1854-7.
15. DNA methylation-based classification of central nervous system tumours. D. Capper, 鈥� , M. Lechner, 鈥� , Pfister SM; Nature. 2018; 555(7697):469-474.
16. Until eradication, awareness. O.S. Jones, C. Vassie, R. Gilson, M. Lechner; The Lancet Infectious Diseases. 2017, 17(4): 368-369听
17. Expanding the benefits of HPV vaccination to boys and men. L. Masterson, J. O'Mahony, M. Lechner; The Lancet. 2017, 388(10063):2992听
18. Human papillomavirus drives tumor development throughout the head and neck: Improved prognosis is associated with an immune response largely restricted to the oropharynx. A. Chakravarthy, 鈥� , M. Lechner, 鈥� , T. Fenton; Journal of Clinical Oncology. 2016, 34(34):4132-4141
19. Health policy: HPV vaccination in boys - will the UK join the fight? L. Masterson and M. Lechner; Nature Reviews of Clinical Oncology. 2016, 13(12):721-722听
20. Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing; G.M. Frampton, 鈥� , M. Lechner, 鈥�, R. Yelensky; Nature Biotechnology. 2013, 10.1038/nbt.2696.
21. Targeted Next-generation Sequencing of Head and Neck Squamous Cell Carcinoma identifies novel genetic alterations in HPV+ and HPV- tumours. M. Lechner, et al.; Genome Medicine. 2013, 5(5): 49.
听
