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¹û¶³Ó°Ôºâ€™s first Advanced Therapies Symposium: Unveiling one of the largest pipelines from lab to market

25 April 2024

¹û¶³Ó°Ôº scientists gathered at the symposium to discuss their research in advanced therapies, from laboratories into commercialisation. The extensive pipelines unveil a huge potential for collaborations with research and commercial partners to bring life-changing impact to patients.

A photo with Prof. Geraint Rees on stage against a screen showing text of ¹û¶³Ó°Ôº Advanced Therapies Symposium.

Photo 1: Professor Geraint Rees, Vice-Provost (Research, Innovation & Global Engagement) at ¹û¶³Ó°Ôº, spoke at the ¹û¶³Ó°Ôº Advanced Therapies Symposium to highlight the unique ecosystem and partnerships built for ¹û¶³Ó°Ôº's ATMP success.

On 24 April, ¹û¶³Ó°Ôº launched its first Advanced Therapies Symposium that attracted over 250 attendees from ¹û¶³Ó°Ôº and beyond, including ¹û¶³Ó°Ôº scientists, research and clinical collaborators, funding entities, and healthcare industry leaders specialising in Advanced Therapy Medicinal Product (ATMP) research and developments.

The ATMP report, released during the symposium, lays out the ¹û¶³Ó°Ôºâ€™s key statistics in its ATMP research and commercialisation projects which represents one of the world’s largest development pipelines for Advanced Therapy Medicinal Products (ATMP). It demonstrates the extensive experimental and clinical expertise spanning across disciplines, highlighting specialisms in Rare Diseases, Ophthalmology, Haematology/Oncology, Neurology, and Immunology.

Key figures from the report include:

  • 100+ projects in development, from discovery, clinical trials through to market launch.
  • Close to £80M in public funding to support the current active projects spanning preclinical stage and Phase I/II trials.
  • One treatment for haemophilia A, ¸é´Ç³¦³Ù²¹±¹¾±²¹²Ôâ„¢, already licenced in the U.S and EU through ¹û¶³Ó°Ôºâ€™s partner Biomarin.
  • 54% of the UK’s entire ATMP academically sponsored clinical trials are conducted via ¹û¶³Ó°Ôº partner hospitals.
  • 43% of the UK’s commercial sponsored trials are delivered by ¹û¶³Ó°Ôº partner hospitals.

The figures underline not just the research excellence of these complex therapies at ¹û¶³Ó°Ôº, but also its leading position in moving the advanced therapy field out of the research laboratories into commercialisation, with approved drugs being delivered to patients.

Over the past 10 years, ¹û¶³Ó°Ôº has successfully spun out twelve advanced therapy companies, which collectively have received in excess of £2Bn of external investment, with five companies having IPO’d.

At the symposium, ¹û¶³Ó°Ôº scientists discussed their expertise in advanced therapies, with a focus on ¹û¶³Ó°Ôº's early-stage research and clinical experience, alongside presentations on successful case studies. Panel discussions on industry and venture capital (VC) investments in spinouts, as well as clinical experience in delivering these complex therapies, inspired immense knowledge exchange on and off the stage.

Chairing the panel discussion on industry and VC investments, Dr. Anne Lane, CEO of ¹û¶³Ó°Ôº Business (¹û¶³Ó°ÔºB), said, "The coordinated support between ¹û¶³Ó°Ôº, ¹û¶³Ó°ÔºB, and its partner hospitals—from science-trained business managers, translational research experts, and clinical facilities and units—creates a unique position for ¹û¶³Ó°Ôº to make every step towards successful commercialisation, helping to de-risk projects and maximise venture capital investment."Ìý

Professor Geraint Rees, Vice-Provost (Research, Innovation & Global Engagement) at ¹û¶³Ó°Ôº, added in his closing remarks, "It is the precious ecosystem we have created over the years and partnerships with various stakeholders – from patients, hospitals, funding, research, and investment partners – that make ¹û¶³Ó°Ôº a global leader in advanced therapies. Our R&D and clinical pipelines are supported by unparalleled commercial pipelines along the translational pathway, enabling us to make a real impact on individual lives."Ìý

The symposium is organised by the ¹û¶³Ó°Ôº Translational Research Office (TRO) and the Therapeutic Innovation Networks (TINs), and chaired by Professor Simon Waddington, Professor of Gene Therapy and Maternal & Fetal Medicine at ¹û¶³Ó°Ôº, who leads the Cell and Gene Therapy network under the TINs.

A photo showing Prof. Simon Waddington on stage

Photo 2: Professor Simon Waddington, Professor of Gene Therapy and Maternal & Fetal Medicine at ¹û¶³Ó°Ôº, kicked off ¹û¶³Ó°Ôºâ€™s first Advanced Therapies Symposium.

A photo showing a group of speakers on stage.

Photo 3:ÌýDr. Anne Lane, CEO of ¹û¶³Ó°Ôº Business, led the panel discussion on industry and venture capital investments in spinouts, joined by Professor Emma Morris (¹û¶³Ó°Ôº), Professor Bobby Gaspar (¹û¶³Ó°Ôº), Dr. Richard Fagan (¹û¶³Ó°ÔºB), and Dr. Elisa Petris (Syncona Investment Management Ltd).

 A photo showing a group of speakers on stage.

Photo 4:ÌýProfessor Dimitri Michael Kullmann, Professor of Clinical and Experimental Epilepsy at ¹û¶³Ó°Ôº Queen Square Institute of Neurology, led the panel discussion on ¹û¶³Ó°Ôºâ€™s clinicians' experience, joined by Professors Amit Nathwani, Sarah Tabrizi, Manju Kurian, and Claire Booth.

A photo showing some people discussing in front of the poster boards
A photo showing some people discussing in front of the poster boards

Photo 5a-b:Ìý¹û¶³Ó°Ôº early career researchers (ECRs) across research disciplines showcased their research posters at the event and exchanged ideas with the attendees.

A group of people networking inside a building
A group of people networking inside a building

Photo 6a-b:ÌýThe ¹û¶³Ó°Ôº Advanced Therapies Symposium presented unprecedented networking opportunities between ¹û¶³Ó°Ôº scientists and its research and industry partners, generating leads for potential collaboration opportunities.

A photo showing a group of audience inside a lecture theatre
A photo showing a group of audience inside a lecture theatre

Photo 7a-b:Ìý¹û¶³Ó°Ôºâ€™s first Advanced Therapies Symposium attracted over 250 attendees from ¹û¶³Ó°Ôº and beyond, including ¹û¶³Ó°Ôº scientists, research and clinical collaborators, funding entities, and healthcare industry leaders specialising in Advanced Therapy Medicinal Product (ATMP) research and developments.Ìý

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Event speakers (In order of appearance at the event):

Session chairs and panellists:

External panellist:

Sponsors:


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