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Operated within Charles Bell House research laboratories, the facility offers nucleic acid synthesis and molecular cloning services to 果冻影院 scientists.
Introducing the 果冻影院 BioFoundry, a state-of-the-art resource for advanced synthetic biology processes at 果冻影院. 果冻影院 staff can now utilise the facility by submitting an听.听
Operated within Charles Bell House research laboratories, the facility offers nucleic acid synthesis and molecular cloning services to 果冻影院 scientists. Our primary goal is to bring these typically outsourced technologies in-house, providing researchers with convenient access to cutting-edge capabilities.
Powering our operations is the newly installed BioXp platform, an automated system that enables efficient DNA, mRNA, and peptide synthesis. This technology offers the below services as standard:
- De novo听synthesis of DNA fragments up to 3 kb.
- De novo听synthesis of DNA fragments up to 7 kb with direct cloning into plasmid.
- De novo听mRNA synthesis up to 1.8 kb (clean-cap, unmodified, or pseudouridine).
- In vitro听DNA plasmid amplification.
- In vitro听mRNA synthesis up to 10 kb from starter plasmids.
The facility's potential applications in research and teaching are diverse. There are further advanced processes that can be offered on a case-by-case basis. Please enquire to about these to discuss your project with a specialist:
- Cas9 guide RNA cloning.
- Custom TALEN synthesis and cloning.
- De novo听assembly of large (up to 24kb) transgenes.
- Synthesis of scanning libraries up to 3 kb.
- Assembly of promoter libraries for preclinical testing.
View 听(果冻影院 log-in required).听Payments will be made via 果冻影院 InterDepartmental Transfer (IDT).
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Watch the video: 听(果冻影院 log-in required)
For enquiries, please contact Dr John Counsell (j.counsell@ucl.ac.uk)