果冻影院

Earlier this year Dr Helen Donoghue, Honorary Lecturer in Clinical Microbiology at 果冻影院, had two papers published in Nature sharing the secrets revealed from the analysis of 18^th century mummies from a Hungarian crypt. The story had a wide impact and was even tweeted by Bill Gates!

Since then the team have had several papers published and Helen recently gave a lunchtime seminar on ancient leprosy to Aix-Marseille University Medical School and in December will be in Oslo to examine a PhD candidate on intestinal tuberculosis.

We're very excited to announce that Helen will be giving a 果冻影院 Lunchtime Lecture on the 17^th of March 2016 titled "Bones, mummies, tuberculosis and ancient DNA". We will give details of this next year.

• Lewandowska, M., G艂adykowska-Rzeczycka, J.J. Molecular studies on ancient聽M. tuberculosis听补苍诲听M. leprae: methods of pathogen and host analysis. European Journal of Clinical Microbiology & Infectious Diseases 34: 1733-1749.
• Donoghue, H.D., Spigelman, M., O'Grady, J.O., Szikossy, I., Pap, I., Lee, O.Y.-C., Wu, H.H.T., Besra, G.S., Minnikin, D.E. (2015) Ancient DNA analysis - an established technique in charting the evolution of tuberculosis and leprosy. Tuberculosis 95: S140-S144. doi: 10.1016/j.tube.2015.02.020
• Hershkovitz, I., Donoghue, H.D., Minnikin, D.E., May, H., Lee, O.Y.-C., Feldman, M., Galili, E., Spigelman, M., Rothschild, B.M., Bar-Gal, G.K. (2015) Tuberculosis origin: the Neolithic scenario. Tuberculosis 95: S122-S126.
• Lee, O.Y.-C., Wu, H.H.T., Besra, G.S., Rothschild, B.M., Spigelman, M., Hershkovitz, I., Kahila Bar-Gal, G., Donoghue, H.D., Minnikin, D.E. (2015) Lipid biomarkers provide evolutionary signposts for the oldest known cases of tuberculosis. Tuberculosis 95: S127-S132.
• Masson, M., Moln谩r, E., Donoghue, H.D., Minnikin, D.E., Lee, O.Y.-C., Wu, H.H.T., Besra, G.S., Bull, I.D., P谩lfi, G. (2015) 7000 year-old tuberculosis cases from Hungary - osteological and biomolecular evidence. Tuberculosis 95: S13-S17.
• Minnikin, D.E., Lee, O.Y.-C., Wu, H.H.T., Besra, G.S., Bhatt, A., Nataraja, V., Rothschild, B.M., Spigelman, M., Donoghue, H.D. (2015) Ancient mycobacterial lipids: key reference biomarkers in charting the evolution of tuberculosis. Tuberculosis 95: S133-S139. doi: 10.1016/j.tube.2015.02.009
• Moln谩r, E., Donoghue, H.D., Lee, O.Y-C., Wu, H.H.T., Besra, G.S., Minnikin, D.E., Bull, I.D., Llewellyn, G., Williams, C.M., Spekker, O., P谩lfi, G. (2015) Morphological and biomolecular evidence for tuberculosis in 8th century AD skeletons from B茅lmegyer-Cs枚m枚ki domb, Hungary. Tuberculosis 95: S35-S41.
• Spigelman, M., Donoghue, H.D., Abdeeb, Z., Ereqat, S., Sarie, I., Greenblatt, C.L., Pap, I., Szikossy, I., Hershkovitz, I., Kahila Bar-Gal, G., Matheson, C. (2015) Evolutionary changes in the genome of Mycobacterium tuberculosis and the human genome from 9000 years BP until modern times. Tuberculosis 95: S145-S149.
• Szikossy, I., P谩lfi, G., Moln谩r, E., Karlinger, K., Kov谩cs, B., Korom, Cs., Schultz, M., Schmidt-Schultz, T., Spigelman, M., Donoghue, H.D., Kust谩r, 脕., Pap, I. (2015) Two positive TB cases in the late Nigrovits family, 18th century V谩c, Hungary. Tuberculosis 95: S69-S72. doi: 10.1016/j.tube.2015.02.015

Helen is also a co-author of an open access book chapter on MTB cell wall lipids with her collaborators from Birmingham:

• Minnikin, D.E., Lee, O.Y.-C., Wu, H.H.T., Nataraj, V., Donoghue, H.D., Ridell, M., Watanabe, M., Alderwick, L., Bhatt, A., Besra, G.S. (2015). Pathophysiological implications of cell envelope structure in Mycobacterium tuberculosis and related taxa. Chapter 7 in Ribon W, Tuberculosis 颅颅- Expanding Knowledge. Intech Open Access Publisher, Rijeka, Croatia, 146-175. ISBN 978-953-51-4194-5.