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Module Outline:

This is an intermediate course designed to provide students who have a primary interest in Medicinal Chemistry and Biochemistry with a more detailed knowledge of Physical Chemistry applied to aqueous solutions. It can also form a bridge to more advanced chemistry courses.

Module Aims:

At the end of the module students should be able to:

1. Understand the basic concepts of thermodynamics as applied to aqueous solutions, especially activities and the use of thermodynamic tables.
2. Apply basic thermodynamics to some simple systems including macromolecule solutions.
3. Understand important concepts in equilibrium electrochemistry and the application of these in chemical and biochemical situations.
4. Understand the concepts of mobility and conductance and the determination of transport properties in solution.
5. Understand basic spectroscopic concepts as applied to species in solution and be able to choose between various spectroscopic techniques for monitoring species in solution.
6. Understand the importance of risk assessment for laboratory practicals and maintain an accurate record in your laboratory notebook.
7. Perform calculations and analysis using data collected in the laboratory, present the data clearly and interpret what it means.

Teaching and Learning Methods:

Lectures: The topics will be introduced through a blended delivery of asynchronous videos with online activities, and support hours.

Workshops: These are timetabled problem-solving workshops to complement the Lecturecast-only lectures. Attendance to these workshops is required after the relevant lecture material has been viewed on Lecturecast. Workshop questions should have been attempted before attending.

Self-study: In addition to timetabled hours it is expected that you engage in self-study in order to master the material. This can take the form of watching the Lecturecast lectures; practicing example questions (workshop questions, additional questions available on Moodle and past exam questions); preparing for laboratory sessions and writing up reports and further reading in textbooks and online.

Laboratories: You will carry out several practicals, each of which support understanding of the module material as well as teaching essential skills for a practicing chemist. As laboratory skills are an essential aspect of this programme, attendance in the laboratory sessions is monitored and compulsory.