果冻影院

The 2022 Osler medal was presented to Prof Tabrizi for her contribution to Huntington鈥檚 disease (HD) translational research after her giving the Osler Medal Lecture at the 115th Annual Meeting of the Association of Physicians of Great Britain & Ireland.

The Association of Physicians of Great Britain and Ireland was founded by William Osler in 1907 to advance medicine 鈥渋n a manner that promotes friendship amongst Physicians鈥�. Every year, the Association awards the Osler Medal to a pre-eminent clinical scientist who epitomises the best of translational research.

Sarah鈥檚 medal lecture was titled 鈥楴ew Genetic Therapies for Neurodegenerative Diseases鈥� and highlighted news of potential treatments for HD and other neurodegenerative diseases.

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听Image:听Prof Sarah Tabrizi giving the Osler medal lecture听听 听 听 听 听 听 听 听 听 听 听 听 听 听 听 听听

The HDSA 2022 Outstanding Research Award recognises contribution to HD translational research. The HDSA has committed more than $20 million to fund research, with the goal of finding effective treatments to slow Huntington鈥檚 disease. Their research efforts have helped to increase the number of scientists working on Huntington鈥檚 Disease and have shed light on many of the complex biological mechanisms involved.

The award was presented to Sarah at the HDSA 37th Annual Convention, where she also gave a on a novel staging framework that assesses HD progression.听 Published in The Lancet Neurology, the new evidenced-based system includes criteria to biologically define HD stages across the whole trajectory of the disease from birth, which has never previously been done before and paves the way for clinical trials of drugs in the earliest phase of disease.

Prof Sarah Tabrizi鈥檚 research programme at the Huntington鈥檚 Disease Centre, 果冻影院 Queen Square Institute of Neurology, and the UK Dementia Research Institute at 果冻影院, seeks to discover effective disease-modifying treatments that prevent or reverse the neurodegenerative process in HD. She leads a research group that follows two distinct but complementary approaches: basic science focusing on cellular mechanisms of neurodegeneration, and a programme to translate those findings into treatments and cures.

鈥淚鈥檓 delighted that Sarah has been awarded the 2022 Osler medal and the HDSA 2022 Research Medal, it is a testament to her dedication to finding an effective disease modifying treatment for patients and families with Huntington鈥檚 disease鈥� Professor Mike Hanna, Director, 果冻影院 Queen Square Institute of Neurology.

Links:

• New system that defines Huntington鈥檚 Disease will 鈥榬evolutionise鈥� drug trials
• Tabrizi et al.听. Lancet Neurology 21(7), P632-644.听Available online 15th June 2022.听
• Huntington鈥檚 Disease Centre, 果冻影院 Queen Square Institute of Neurology

Main Image:听Prof Sarah Tabrizi receiving the HDSA 2022 Research Award